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KMID : 0363220090470050583
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Korean Journal of Dermatology
2009 Volume.47 No. 5 p.583 ~ p.587
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A Case of Zosteriform Kaposi`s Sarcoma after Prednisolon Treatment
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Kim Cheol-Hann
Kim Dae-Hyun
Jeon Jin-Seok
Kang Sang-Gue
Kim Dong-Wook
Cho Moon-Kyun
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Abstract
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Kaposi’s sarcoma is a rare lympho-angioproliferative neoplasm with four types of variants: classic, iatrogenic immunosuppressive drug-associated, AIDS-related and Africa-endemic Kaposi’s sarcoma. Most immunosuppressive drug- associated Kaposi’s sarcomas usually occur after a kidney transplant or after receiving immunosuppressive therapy. A 64-year-old female patient showed numerous purpuric nodules and smaller erythematous plaques on the right lower leg for three months. Previously, the patient was treated with an immunosuppressive drug for rapidly progressive glomerulonephritis for a five-week period. A skin biopsy was performed under the clinical diagnosis of Kaposi’s sarcoma. We performed immunohistochemical staining and polymerase chain reaction to detect human herpes virus 8 (HHV-8). We report a case of iatrogenic immunosuppressive drug-associated zosteriform Kaposi’s sarcoma that rapidly occurred five weeks after prednisolon therapy in a rapidly progressive glomerulonephritis patient.
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KEYWORD
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Human herpes virus 8, Iatrogenic immunosuppressive drug-associated Kaposi`s sarcoma, Kaposi`s sarcoma, Zosteriform Kaposi`s sarcoma
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